Zoladex LA® (10.8mg) for men (goserelin acetate)
Alternative brand (trade) names: Zoladex
What is Zoladex LA® (10.8mg) for men ?
Zoladex LA (10.8mg) is a hormonal anti-cancer drug, which contains the medicine goserelin acetate. It is a longer acting formulation of Zoladex 3.6mg.
What is Zoladex LA® (10.8mg) for men used for?
In men, Zoladex LA (10.8mg) is used for the treatment of hormone-sensitive prostate cancer, either alone or in combination with other treatments depending on how advanced the disease is.
How does Zoladex LA® (10.8mg) for men work ?
Zoladex LA (10.8mg) is a member of the anti-hormonal group of medicines:
- Hormones are natural chemical signals, which are released by different parts of the body and can be carried in the blood to some other area to have an effect.
- Hormonal therapy involving treatment with Zoladex, which is an analogue of an endocrine hormone called Luteinising Hormone. Releasing Hormone, (LHRH), stops the production by the testes of male sex hormones, including testosterone.
- Testosterone is a sex hormone, which at certain stages of prostate cancer helps promote the growth of the tumour.
- Zoladex works by blocking the production of testosterone and therefore reduces the levels of the male hormone. This stops or slows the growth of cancer cells and is sometimes called medical castration.
How is Zoladex LA® (10.8mg) for men given ?
Zoladex LA (10.8mg) is given as an injection of a cylindrical pellet (equivalent to 10.8mg goserelin acetate) under the skin of the lower abdomen (body trunk) and lasts for 3 months.
Zoladex works because the pellet, (which is usually referred to as a depot formulation), slowly dissolves to release the medicine which is then absorbed by the body over the period of 3 months at which point another depot will be injected.
Alternative brand (trade) names include Zoladex 10.8mg.
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