CRESTOR contains the medicine rosuvastatin, which belongs to a group of medicines known as HMG-CoA reductase inhibitors, or ‘statins’.
What is CRESTOR™ used for?
CRESTOR is used to modify abnormal levels of fatty substances in the blood called lipids, mainly high levels of cholesterol and triglycerides. CRESTOR is used in combination with a diet plan when changes to diet and exercise alone have failed to lower high cholesterol and triglycerides.
How does CRESTOR™ work ?
Rosuvastatin belongs to a group of medicines known as HMG-CoA reductase inhibitors, or ‘statins’.
HMG-CoA reductase is an enzyme (chemical) in the body which converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, which is then converted to cholesterol.
By inhibiting HMG-CoA reductase, CRESTOR reduces the total amount of cholesterol produced by the body.
There are 2 types of cholesterol in the blood, LDL-cholesterol (“Bad Cholesterol”) and HDL-cholesterol (“Good cholesterol”)
By inhibiting HMG-CoA reductase, CRESTOR results in lower levels of (“Bad”) LDL-cholesterol and reduces triglycerides in the blood.
CRESTOR also leads to increased levels of (“Good”) HDL-cholesterol in the blood.
How is CRESTOR™ given ?
CRESTOR is available as a once a day tablet which may be given at any time of day and can be taken with or without food.
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