• Go to navigation
  • Go to content
Patient Health International

You are here

  • Home
  • AstraZeneca medicines
  • Tenoretic® (atenolol/chlorthalidone)

Astrazeneca global websites

  • AstraZeneca Websites

Main navigation

  • Home
  • News & feature articles
  • Body map
  • List of health conditions
  • Interactive area
  • About medicines
  • AstraZeneca medicines
  • About clinical trials
  • Glossary
  • Links
  • Sitemap

Tenoretic® (atenolol/chlorthalidone)

Alternative brand (trade) names: Tenoret 50.

What is Tenoretic® ?

Tenoretic contains a combination of two medicines called atenolol and chlorthalidone.

What is Tenoretic® used for?

It is used to treat high blood pressure (hypertension).

How does Tenoretic® work ?

Tenoretic combines two medicines that have different ways of working and leads to greater lowering of blood pressure in more people than with either medicine used alone:

Atenolol belongs to a group of medicines called beta-blockers.

  • It works by blocking the action of a chemical called noradrenaline, which is released from nerves in the heart to control its rhythm.

  • Atenolol also blocks another chemical called adrenaline, which is a hormone (chemical signal carried in the blood) that has similar effects to noradrenaline.

  • Atenolol does this by stopping these chemicals from attaching (binding) to sites, called beta-receptors, in the heart so they can’t produce their effects.

  • Atenolol therefore reduces the heart rate and the force of heart muscle contraction and lowers blood pressure.

Chlorthalidone is a diuretic (water pill).

  • It works by reducing the kidney’s ability to hold on to water and sodium (salt) and increasing the output of urine (diuresis) and salt. This in turn lowers the blood pressure.

How is Tenoretic® given ?

It is supplied as tablets, and is taken only once daily.

It is very important to take medicines for high blood pressure as often as your doctor has told you to, even if you do not feel ill. This is because high blood pressure, if not treated, can lead progressively to diseases of the heart and blood vessels and eventually to very serious illness, such as a heart attack or stroke.

It is also important to follow any lifestyle instructions that your doctor has given to you, like trying to give up smoking, reducing your weight, doing more exercise and eating a healthy diet.

Country specific information

To consult your local information.

Any medical information on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. Read more important information.

Back to search

  • Advanced search

Quick links

  • AstraZeneca US
  • Investor information
  • Press information

Page tools

  • Print
  • Bookmark this page

Related links

  • Other countries

List of conditions


AstraZeneca medicines

AstraZeneca International

Legal notices

  • Legal notice
  • Privacy policy
  • © AstraZeneca 2010